Riders will cycle through bush tunnels, pine single tracks and bushveld trails, and will be rewarded with spectacular views.
The race is one of five series under the Mpumalanga Marathon Series, which are open to mountain bikers from all provinces.
For the Sappi Mankele MTB Challenge, participants can choose anything from a 2.4km lap to the ultimate 70km trail.
Entries are still open. Participants are welcome to bring their families and friends along to enjoy treats from the food stalls, awesome entertainment and a kiddies' play area.